Wydawnictwo Medyczne Mediton

Under the scientific patronage of

the Polish Society of Audiology and Phoniatrics


Original articles

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The influence of the hydroxyzine on the recording quality of the cervical Vestibular Evoked Myogenic Potential (cVEMP)
Dagmara Zaborowska 1/, Dana Pavlovschi 1/, Monika Woźniak 2/, Karolina Dżaman 2/, Igor Anurin 1/, Ireneusz Kantor 2/
  • 1/ Zespół Oddziałów Otolaryngologii, Mazowiecki Szpital Bródnowski, Warszawa
  • 2/ Klinika Otolaryngologiczna, Centrum Medyczne Kształcenia Podyplomowego, Warszawa

Introduction. The cervical Vestibular Evoked Myogenic Potential (cVEMP) is an objective and non-invasive test that evaluates the state of otolithic organs. The disadvantage of this method is the impact of multiple factors on the quality of the recording, including excessive muscle tension and stress during the examination.
Aim. The aim of the study is to assess the effect of the drug containing hydroxyzine hydrochloride on the quality of the results of the cVEMP examination.
Material and methods. The study included 50 patients treated for vestibular disorders of various etiologies with „low quality of the cVEMP result”. The patients were qualified for a reexamination 2h after oral one-time administration of the drug containing 25 mg of hydroxyzine hydrochloride.
Results. In the second examination the improvement of the results’ morphology was observed in 22 (44%) patients, the same results as in the initial examination – in 21 (42%) patients. In 7 (14%) patients results obtained in the second examination were more difficult to interpret.. The analysis of latency and amplitude of p1 and n1 waves did not show significant difference in the examination before and after administration of hydroxyzine hydrochloride
Conclusion. For the improvement in the quality of cVEMP recording it seems advisable to administer hydroxyzine hydrochloride prior to the examination in order to calm the patient and decrease muscle tension.

Otorynolaryngologia vol 17. no 4. Dcemberpages: from 179to 185
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