Wydawnictwo Medyczne Mediton

Under the scientific patronage of

the Polish Society of Audiology and Phoniatrics


Review articles

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Side effects of radiotherapy in patients with head in neck cancer: mechanisms and consequences
Ewa Ziółkowska 1/, Marta Biedka 2/, Wiesława Windorbska 3/
  • 1/ Oddział Radioterapii 1, Centrum Onkologii w Bydgoszczy
  • 2/ Oddział Radioterapii 1, Centrum Onkologii w Bydgoszczy, Katedra Onkologii i Klinika Brachyterapii UMK w Toruniu, Collegium Medicum w Bydgoszczy
  • 3/ Zakład Teleterapii, Centrum Onkologii w Bydgoszczy

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide and often is associated with a poor prognosis. Therapeutic decisions are usually based on clinical pathological parameters like stage of clinical progression, location of tumour and its histological grading, as well as patient’s general condition. The role of radiotherapy in the treatment of head and neck cancer patients is essential because its effectiveness is comparable to that of surgery, and it allows to preserve the organ. During radiotherapy, patients with advanced head and neck cancer very often require aggressive method of irradiation, such as high total dose and/or concomitant chemotherapy. The irradiation affects not only the tumour, but also the normal neighboring tissues. During radiotherapy of head and neck cancer patients, symptoms of acute mucosal reaction are major factors in the determination of tolerance and completeness of treatment.

The aim of this study is to make the clinicians aware of the side effects of radiotherapy in patients with HNSCC and of the problems that may arise during their treatment.

Otorynolaryngologia vol 10. no 4. Decemberpages: from 147to 153
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