Wydawnictwo Medyczne Mediton

Under the scientific patronage of

the Polish Society of Audiology and Phoniatrics


Original articles

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Localisation and treatment of head and neck region granular cell tumour
Jarosław Markowski 1/, Tatiana Gierek 1/, Jacek Pająk 2/, Ewa Zielińska-Pająk 2/, Małgorzata Witkowska 1/, Katarzyna Pasternak 1/, Piotr Wardas 3/, Karina Podlejska 1/
  • 1/ Katedra i Klinika Laryngologii Śląskiego Uniwersytetu Medycznego w Katowicach
  • 2/ Zakład Histopatologii Katedry Morfologii Śląskiego Uniwersytetu Medycznego w Katowicach
  • 3/ Oddział Laryngologii Szpitala Miejskiego w Sosnowcu

Granular cell tumour, first described in 1929 by Aleksey Abrikossoff, is a rare tumour developing from Schwann cells of the peripheral nerve sheath. The Abrikossoff tumour develops usually between the 4th and 5th decade of life. Head and neck – especially lateral part of tongue, buccal mucosa, larynx and oesophagus – is the most common location of these lesions. The clinical symptoms depend on tumour location and size.

To assess location and treatment results of granular cell (Abrikossoff) tumours of the head and neck region.

Material and methods.
A retrospective analysis has been performed of medical documentation of 8 patients treated between 2000 and 2005 for granular cell tumours. At the moment of hospitalisation, the age of the patients ranged from 32 to 60 years. Case histories, surgery protocols, and documents obtained from the otolaryngology outpatient clinic were analysed.

Among the study subjects, there were four cases of tumour located on the tongue, three in the larynx and one in the oesophagus. Histopathological examination showed that the Abrikossoff tumour was benign in all cases. Radical tumour dissection was performed in all patients. Up to now, the followup has not revealed any signs of the recurrence in the treated patients.

Abrikossoff tumour, though rare, should be taken in consideration during differential diagnosis of head and neck lesions. The prognosis for granular cell tumour is good, and complete removal of the lesions ensures full recovery in most cases.

Otorynolaryngologia vol 10. no 4. Decemberpages: from 164to 170
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